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The role of autocrine transforming growth factor alpha in Epidermal Growth Factor receptor mediated tumorigenicity

โœ Scribed by A. Rajput; J. Wang; J. Foster; D. Dawson; J. Willis; M. Brattain; J. Willson


Book ID
116702112
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
97 KB
Volume
130
Category
Article
ISSN
0022-4804

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โœ Xiaomei Ouyang; Timothy Gulliford; Guocai Huang; Richard J. Epstein ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 153 KB ๐Ÿ‘ 2 views

Transforming growth factor-alpha (TGFโฃ) is an epidermal growth factor receptor (EGFR) ligand which is distinguished from EGF by its acid-labile structure and potent transforming function. We recently reported that TGFโฃ induces less efficient EGFR heterodimerization and downregulation than does EGF (