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The role of aldehyde reductase AKR1A1 in the metabolism of gamma-hydroxybutyrate in 1321N1 human astrocytoma cells

✍ Scribed by Samar Alzeer; Elizabeth M. Ellis

Book ID
113518363
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
417 KB
Volume
191
Category
Article
ISSN
0009-2797

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The functional significance of the 2- and 3-hydroxyl groups of 1 D-myo-inositol 1,4,5-trisphosphate [Ins(1,4,5)P3] was probed by using Ins(1,4,5)P3 analogues variously modified at positions 2 and 3 or elsewhere. The intrinsic activities of these compounds were compared to that of Ins(1,4,5)P3, using