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Goniodomin A, an Antifungal Polyether Macrolide, Increases the Filamentous Actin Content of 1321N1 Human Astrocytoma Cells

โœ Scribed by KOUICHI MIZUNO; NORIMICHI NAKAHATA; EMIKO ITO; MASAHIRO MURAKAMI; KATSUMI YAMAGUCHI; YASUSHI OHIZUMI

Book ID
118111257
Publisher
Pharmaceutical Press
Year
1998
Tongue
English
Weight
436 KB
Volume
50
Category
Article
ISSN
2042-7158

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Goniodomin A, an antifungal polyether ma
Goniodomin A, an antifungal polyether macrolide, exhibits antiangiogenic activities via inhibition of actin reorganization in endothelial cells
โœ Mayumi Abe; Daisuke Inoue; Kimihiro Matsunaga; Yasushi Ohizumi; Hiroshi Ueda; To ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 371 KB

## Abstract Goniodomin A (GDA) is an antifungal polyether macrolide isolated from the dinoflagellate __Goniodoma pseudogoniaulax__. Previous studies revealed that GDA profoundly affected cytoskeletal reorganization. We examined the effect of GDA on the angiogenic properties of vascular endothelial