The ring-opening of an unsymmetrical tetrahedral intermediate - 2-hydroxy-1,3-oxathiolane
โ Scribed by Linda J. Santry; Raymond A. Poirier; Robert A. McClelland; Imre G. Csizmadia
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 438 KB
- Volume
- 65
- Category
- Article
- ISSN
- 1432-2234
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๐ SIMILAR VOLUMES
Studies on an unexpected reaction involving a reductive cleavage of the pyridazine moiety of a tricyclic heterocycle are described. Structure assignments for the products obtained from the reductive cleavage were made using physicochemical methods. The pro drug' (TCN-P, fi) of 6-amino-4-N-methyl-8-(
Hantxsch cyclization of cyanoethyl3-aminwrotonate and (E,Z)-4dialkoxymethyl-2-benzylidene-acetoacetates (5a,b) afforded-3,4-rrons-2-hydroxy-l.2,3,4-tcuahydropyridine (Ya,b) in high stereoselectivity. In the last decade, synthetic studies of 1,4dihydropyridine derivatives have been carried out in man
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