The relevance of glial monoamine oxidase-B and polyamines to the action of selegiline in parkinson's disease
β Scribed by Prof. M. B. H. Youdim; P. Riederer
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 513 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0885-3185
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π SIMILAR VOLUMES
## Monoamine oxidase B (MAO -B ) is an enzyme that has relevance for Parkinson disease (PD) because of its roles in catabolizing dopamine and potentially activating exogenous neurotoxicants. A polymorphism of the gene encoding MAO-B has been identified as a single base change (A or G) in intron
## Abstract Cigarette smoking is associated with reduced monoamine oxidase B (MAO B) activity. Polymorphisms of the __MAO B__ gene may modify the relationship between smoking and Parkinson's Disease (PD). We examined the association of MAO B intron 13 G/A polymorphism and risk of PD, and the modula