The monoamine oxidase B gene GT repeat polymorphism and Parkinson’s disease in a Chinese population
✍ Scribed by G. D. Mellick; D. D. Buchanan; P. A. Silburn; D. K. Y. Chan; D. G. Le Couteur; L. K. Law; J. Woo; C. P. Pang
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 31 KB
- Volume
- 247
- Category
- Article
- ISSN
- 0340-5354
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Cigarette smoking is associated with reduced monoamine oxidase B (MAO B) activity. Polymorphisms of the __MAO B__ gene may modify the relationship between smoking and Parkinson's Disease (PD). We examined the association of MAO B intron 13 G/A polymorphism and risk of PD, and the modula
## Monoamine oxidase B (MAO -B ) is an enzyme that has relevance for Parkinson disease (PD) because of its roles in catabolizing dopamine and potentially activating exogenous neurotoxicants. A polymorphism of the gene encoding MAO-B has been identified as a single base change (A or G) in intron
We investigated the association of Parkinson's disease (PD) with dopamine transporter-1 (DAT1), monoamine oxidase-B (MAO-B), and catechol-O-methyltransferase (COMT) gene polymorphisms. Overall, we observed no significant association of PD with the DAT1-3'-variable numbers of tandem repeats, the MAO-
## Abstract The allele G of the intron 13 G/A polymorphism of the monoamine oxidase B gene (MAO‐B) has been associated with Parkinson's disease (PD) in several studies. Apart from a potential direct effect on splicing processes, the association of this intronic polymorphism with PD is due possibly