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The Relationship of Myelin Basic Protein (Arginine) Methyltransferase to Myelination in Mouse Spinal Cord

โœ Scribed by A. J. Crang; W. Jacobson

Book ID
111171769
Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
391 KB
Volume
39
Category
Article
ISSN
0022-3042

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Sinefungin, a known inhibitor of protein methylation, inhibited the myelin basic protein (arginine) methyltransferase activity in homogenates of cultured cerebral cells from embryonic mice. Fifty percent inhibition was achieved with 25pM sinefungin. Electron microscopic examination of the myelin fra