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The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein

โœ Scribed by Zhaohui Feng; Arnold J. Levine


Book ID
113926499
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
352 KB
Volume
20
Category
Article
ISSN
0962-8924

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Cell growth and proliferation requires an intricate coordination between the stimulatory signals arising from nutrients and growth factors and the inhibitory signals arising from intracellular and extracellular stresses. Alteration of the coordination often causes cancer. In mammals, the mTOR (mamma