The coordinate regulation of the p53 and
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Feng, Z.; Zhang, H.; Levine, A. J.; Jin, S.
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Article
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2005
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National Academy of Sciences
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English
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Cell growth and proliferation requires an intricate coordination between the stimulatory signals arising from nutrients and growth factors and the inhibitory signals arising from intracellular and extracellular stresses. Alteration of the coordination often causes cancer. In mammals, the mTOR (mamma