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The regulation of adenylate cyclase in liver membranes of lean and obese mice

✍ Scribed by Bégin-Heick, Nicole; Welsh, JoEllen

Book ID
123434842
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
793 KB
Volume
59
Category
Article
ISSN
0303-7207

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✍ R. R. French; D. A. York 📂 Article 📅 1984 🏛 Springer 🌐 English ⚖ 719 KB

Adenylate cyclase activity was determined using a purified plasma membrane fraction prepared from isolated adipocytes by a Percoll gradient centrifugation procedure. The activation of adenylate cyclase by isoprenaline was reduced by approximately 50% in membranes from obese mice, although no reducti