The regulation of adenylate cyclase in a
The regulation of adenylate cyclase in adipocyte plasma membrane from genetically obese (ob/ob) mice
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R. R. French; D. A. York
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Article
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1984
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Springer
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English
β 719 KB
Adenylate cyclase activity was determined using a purified plasma membrane fraction prepared from isolated adipocytes by a Percoll gradient centrifugation procedure. The activation of adenylate cyclase by isoprenaline was reduced by approximately 50% in membranes from obese mice, although no reducti