The gene responsible for the development
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William F. Benedict; Yuen-kai T. Fung; A. Linn Murphree
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Article
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1988
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John Wiley and Sons
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English
β 494 KB
The gene responsible for the formation of both retinoblastoma and osteosarcoma recently has been isolated. This represents the first human recessive cancer gene ever cloned. Structural deletions within one or both retinoblastoma gene alleles were commonly noted in the retinoblastomas and an osteosar