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The Rate of Mutation of the Gene Responsible for Retinoblastoma in Man

✍ Scribed by Neel, J. V.; Falls, H. F.


Book ID
121144486
Publisher
American Association for the Advancement of Science
Year
1951
Tongue
English
Weight
237 KB
Volume
114
Category
Article
ISSN
0036-8075

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The gene responsible for the development
✍ William F. Benedict; Yuen-kai T. Fung; A. Linn Murphree πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 494 KB

The gene responsible for the formation of both retinoblastoma and osteosarcoma recently has been isolated. This represents the first human recessive cancer gene ever cloned. Structural deletions within one or both retinoblastoma gene alleles were commonly noted in the retinoblastomas and an osteosar