The aim of this report is to present a case of Myelodysplastic syndrome (MDS) who presented, during AML transformation, a step-wise genetic progression that corroborates the two hit model of leukemogenesis. A RCDM-RS (WHO)/RARS (FAB) patient with normal karyotype at diagnosis, evolved into AML after
Retinoblastoma mutation rate in New Zealand and support for the two-hit model
β Scribed by P. H. Fitzgerald; Joanna Stewart; R. D. Suckling
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 263 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0340-6717
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