S. cerevisiae mutants lacking VPS4 missort several vacuolar proteins to the extracellular space, including carboxypeptidase (CPY), vacuolar protease A (PrA), and vacuolar protease B (PrB). In addition, certain soluble secretory proteins, such as invertase and acid phosphatase, are missorted from the
The protein secretory pathway of Candida albicans
β Scribed by William A. Fonzi
- Book ID
- 108916665
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 185 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0933-7407
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## Abstract The gene of protein phosphatase Z1 (Ca__PPZ1__)^1^ that codes a fungus specific regulatory enzyme was investigated in __Candida albicans__. After cloning and sequencing Ca__PPZ1__ we revealed the heterozygous nature of the ATCC 10231 reference strain, and identified two new alleles term