The protective effect of erdosteine on vancomycin-induced pancreatic damage in rats
โ Scribed by Ahmet Koyu; Osman Gokalp; Faruk Oktem; Soner Donmez; Mustafa Dogan; Nermin Karahan; Nurhan Gumral; Nigar Yilmaz; Ahmet Kocak
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 351 KB
- Volume
- 331
- Category
- Article
- ISSN
- 0300-8177
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## Abstract The usefulness of doxorubicin (DXR) is limited by its cardiotoxicity. In order to improve future DXR therapy by using a new antioxidant agent, an experimental study was designed. This study was undertaken to determine whether DXRโinduced cardiotoxicity is prevented by erdosteine, a muco
Reactive oxygen species and cytokines have been implicated in the nephrotoxicity induced by doxorubicin. The goal of the present study was to determine protective effect of aminoguanidine on doxorubicin-induced nephrotoxicity in rats. Different groups of male Wistar rats received doxorubicin (67.75