Protective effect of cinnamaldehyde on streptozotocin-induced damage in rat pancreatic β-cells
✍ Scribed by Hai Dan Yuan; Bo Huang; Sung Hyun Chung
- Publisher
- The Korean Society of Food Science and Technology
- Year
- 2011
- Tongue
- English
- Weight
- 417 KB
- Volume
- 20
- Category
- Article
- ISSN
- 1226-7708
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## Abstract The aim of the present study was to evaluate the possible protective effects of __Nigella sativa__ L. (NS) against β‐cell damage from streptozotocin (STZ)‐induced diabetes in rats. STZ was injected intraperitoneally at a single dose of 50 mg/kg to induce diabetes. NS (0.2 ml/kg/day, i.p
In studies to evaluate possible inhibitors of the B-cell toxin, streptozotocin, the superoxide scavenger, superoxide dismutase, did not prevent or reduce the toxic effects of streptozotocin as determined by loss of insulin secretion from rat pancreatic B cells in monolayer culture. However, 1,1-dime