Intramolecular carbometallation of grign
โ
Sadao Fujikura; Masaharu Inoue; Kiitiro Utimoto; Hitosi Nozaki
๐
Article
๐
1984
๐
Elsevier Science
๐
French
โ 193 KB
Reaction of 6-bromo-l-trimethylsilyl-l-hexyne with magnesium affords the corresponding Grignard reagent whose C-Mg bond intramolecularly adds to the trimethylsilylacetylene moiety in 5-Exo-Dig manner and suprafacially. The reaction can be applied to the synthesis of some cycloalkanes having stereode