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The protection of terminal ethynyl groups in Grignard syntheses

โœ Scribed by Eaborn, C.; Thompson, A. R.; Walton, D. R. M.


Book ID
120651919
Publisher
The Royal Society of Chemistry
Year
1967
Tongue
English
Weight
279 KB
Category
Article
ISSN
0022-4952

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Intramolecular carbometallation of grign
โœ Sadao Fujikura; Masaharu Inoue; Kiitiro Utimoto; Hitosi Nozaki ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 193 KB

Reaction of 6-bromo-l-trimethylsilyl-l-hexyne with magnesium affords the corresponding Grignard reagent whose C-Mg bond intramolecularly adds to the trimethylsilylacetylene moiety in 5-Exo-Dig manner and suprafacially. The reaction can be applied to the synthesis of some cycloalkanes having stereode