๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

The protection of hydroxyl groups in diribonucleoside phosphates

โœ Scribed by J. Smrt


Publisher
Elsevier Science
Year
1967
Tongue
French
Weight
99 KB
Volume
8
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

โœฆ Synopsis


The internucl,eotidic linkage in the ribose series is readily split both in alkaline and in acid media 1 . In an acid medium the hydrolysis of the


๐Ÿ“œ SIMILAR VOLUMES


Selective protection of hydroxyl groups
โœ Kelvin K. Ogilvie; Elaine A. Thompson; Michael A. Quilliam; John B. Westmore ๐Ÿ“‚ Article ๐Ÿ“… 1974 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 157 KB

The chemical synthesis of oligonucleotides requires the availability of versatile reagents for protecting the hydroxyl and amino groups of nucleosides. We have recently described (1) the tert-butyldimethylsilyl (TBDNS) group as an exceedingly useful group for protecting the hydroxyl functions of nuc