The use of silyl groups in protecting the hydroxyl functions of ribonucleosides
β Scribed by Kelvin K. Ogilvie; Krishan L. Sadana; Elaine A. Thompson; Michael A. Quilliam; John B. Westmore
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- French
- Weight
- 126 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0040-4039
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During our investigations into the synthesis and identification of nucleosides and nucleotides we have been seeking versatile hydroxyl-blocking groups for use in the synthesis of oligonucle-
## Abstract magnified image We describe basic chemical properties of 4,5βdi(ethoxycarbonyl)β1,3βdioxolanβ2βyl (DECDO) in view of its use as a protecting group for the 2β²βhydroxyl function of ribonucleosides. The DECDO group is found to be compatible with the DMTr strategy for the currentlyβused ol