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The proteasome and its role in nuclear protein maintenance

โœ Scribed by Nicolle Bader; Tobias Jung; Tilman Grune


Book ID
113614984
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
350 KB
Volume
42
Category
Article
ISSN
0531-5565

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## Abstract The generation of free radicals and the resulting oxidative modification of cell structures are omnipresent in mammalian cells. This includes the permanent oxidation of proteins leading to the disruption of the protein structure and an impaired functionality. In consequence, these oxidi