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The properties of peptidyl diazoethanes and chloroethanes as protease inactivators

โœ Scribed by Peter Wikstrom; Heidrun Kirschke; Stuart Stone; Elliott Shaw


Book ID
115707999
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
731 KB
Volume
270
Category
Article
ISSN
0003-9861

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Peptidyl methylcoumarin amides are well established as model substrates for understanding protease specificity, but the corresponding methylcoumarin esters have attracted scant attention despite their potential utility in active-site titration and mechanistic characterization. We have devised techni