✦ LIBER ✦

ChemInform Abstract: Design and Synthesis of Novel Protease Inhibitors. Tripeptide α′, β′-Epoxyketones as Nanomolar Inactivators of the Proteasome.

✍ Scribed by A. SPALTENSTEIN; J. J. LEBAN; J. J. HUANG; K. R. REINHARDT; O. H. VIVEROS; J. SIGAFOOS; R. CROUCH

Book ID: 112033074
Publisher: John Wiley and Sons
Year: 2010
Weight: 29 KB
Volume: 27
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199624201

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Design and synthesis of novel protease i

Design and synthesis of novel protease inhibitors. Tripeptide α′,β′-epoxyketones as nanomolar inactivators of the proteasome

✍ Andrew Spaltenstein; Johann J. Leban; Jim J. Huang; Kelli R. Reinhardt; O. Humbe 📂 Article 📅 1996 🏛 Elsevier Science 🌐 French ⚖ 272 KB

ChemInform Abstract: Design and Synthesi

ChemInform Abstract: Design and Synthesis of α,β-Epoxyketones as New Anticancer Agents.

✍ Zhengyue Ma; Xinghua Zhang; Shikui Wang; Yang He; Gengliang Yang; Beilei Li; Jun 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 28 KB 👁 1 views

## Abstract Darzens condensation under optimized conditions gives novel α,β‐epoxyketones (III) and (V) which are evaluated for their anticancer activity in vitro.

Design, synthesis and biological evaluat

Design, synthesis and biological evaluation of novel tripeptidyl epoxyketone derivatives constructed from β-amino acid as proteasome inhibitors

✍ Zhang, Jiankang; Cao, Jiayi; Xu, Lei; Zhou, Yubo; Liu, Tao; Li, Jia; Hu, Yongzho 📂 Article 📅 2014 🏛 Elsevier Science 🌐 English ⚖ 585 KB

ChemInform Abstract: Design and Synthesi

ChemInform Abstract: Design and Synthesis of Novel [60]Fullerene Derivatives as Potential HIV Aspartic Protease Inhibitors.

✍ Gian Luca Marcorin; Tatiana Da Ros; Sabrina Castellano; Giorgio Stefancich; Iren 📂 Article 📅 2001 🏛 John Wiley and Sons ⚖ 25 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

ChemInform Abstract: Design and Synthesi

ChemInform Abstract: Design and Synthesis of Monocyclic β-Lactams as Mechanism-Based Inhibitors of Human Cytomegalovirus Protease.

✍ A. D. BORTHWICK; G. WEINGARTEN; T. M. HALEY; M. TOMASZEWSKI; W. WANG; Z. HU; J. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views

Design and Synthesis of Monocyclic β-Lactams as Mechanism-Based Inhibitors of Human Cytomegalovirus Protease. -Starting from monocyclic β-lactams novel human cytomegalovirus protease inhibitors, e.g. (III), (VII),and (VIII), are developed. The most potent one among them is the derivative (VII) with

ChemInform Abstract: Design and Synthesi

ChemInform Abstract: Design and Synthesis of Dipeptidyl α′,β′-Epoxy Ketones, Potent Irreversible Inhibitors of the Cysteine Protease Cruzain.

✍ W. R. ROUSH; F. V. GONZALEZ; J. H. MCKERROW; E. HANSELL 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB 👁 1 views