## Design and Synthesis of α,β-Epoxyketones as New Anticancer Agents Ma, Zhengyue(马正月) Zhang, Xinghua(张兴华) Wang, Shikui(王士奎) He, Yang(何洋) Yang, Gengliang\*(杨更亮) Li, Beilei(李蓓蕾) Yang, Junjie(杨俊杰) Lu, Yuejuan(鲁悦娟) Sun, Jiewei(孙杰威)
ChemInform Abstract: Design and Synthesis of α,β-Epoxyketones as New Anticancer Agents.
✍ Scribed by Zhengyue Ma; Xinghua Zhang; Shikui Wang; Yang He; Gengliang Yang; Beilei Li; Junjie Yang; Yuejuan Lu; Jiewei Sun
- Publisher
- John Wiley and Sons
- Year
- 2011
- Weight
- 28 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Darzens condensation under optimized conditions gives novel α,β‐epoxyketones (III) and (V) which are evaluated for their anticancer activity in vitro.
📜 SIMILAR VOLUMES
## Abstract Dipolar cycloaddition of nitrile oxides, nitrones, and azides to the exocyclic double bond of parthenin (I) generates a library of spiro derivatives (III)—(V) (no yields given).
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
## Abstract A series of novel γ‐carboline ketones (I) is designed, synthesized and evaluated for their cytotoxic activity against several human cancer cell lines.