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The presence and active transcription of three independent leader exons in the mouse insulin-like growth factor II gene

✍ Scribed by Koji Ikejiri; Masato Furuichi; Takaki Ueno; Tetsuya Matsuguchi; Takahashi Keikichi; Hideya Endo; Mikio Yamamoto


Book ID
119120052
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
439 KB
Volume
1089
Category
Article
ISSN
0167-4781

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Insulin-like growth factor II (IGF-II) plays significant roles in the growth and development of mammals through the regulation of mitogenesis and cell survival. Previously, IGF-II mRNA transcripts within the CNS were detected in the choroid plexus and leptomeninges (DeChiara et al., 1991). The objec