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The Alcohol-Induced Suppression of Ovarian Insulin-Like Growth Factor-1 Gene Transcription Is Independent of Growth Hormone and Its Receptor

✍ Scribed by Vinod K. Srivastava; Jill K. Hiney; Julie A. Mattison; Andrej Bartke; W. Les Dees


Book ID
109123757
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
144 KB
Volume
31
Category
Article
ISSN
0145-6008

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## Abstract WWP1, a HECT type E3 ubiquitin ligase frequently amplified and overexpressed in breast cancer, has the potential to become a useful clinical biomarker and therapeutic target in breast cancer. Here, we performed immunohistochemical staining in formalin‐fixed and paraffin‐embedded tissue