## Abstract The pyrolysis of citric acid‐1, 5‐^14^C~2~ under controlled conditions and subsequent hydrolysis of the anhydride initially produced yields principally 2‐methylenebutanedioic acid‐4‐^14^C (citaconic acid‐^14^C), together with a minor amount of cis‐2‐methylbutenedioic acid‐4‐^14^C (citra
The preparation of 2-(4-chlorophenyl)-[2-14C]thiazol-4-ylacetic acid [I.C.I. 54,450]
✍ Scribed by D. F. White; J. Burns
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- French
- Weight
- 257 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
The preparation of 2‐(4‐chlorophenyl)‐[2‐^14^C]thiazol‐4‐ylacetic acid [I.C.I. 54,450] from potassium [^14^C] cyanide in six stages is described. The overall radioachemical yield of product, at a specific activity of 12.56 μCi/mg, was 22.2%.
📜 SIMILAR VOLUMES
## Abstract A relatively simple route to 2‐substituted adamantane derivatives labelled with ^14^C at the 2‐position in the adamantane skeleton was developed. The approach used (Figure I) involved ring expansion of adamantanone by labelled diazomethane, conversion of the resulting 4‐homoadamantanone
## Abstract 7‐Chloro‐5‐(2‐chlorophenyl)‐1,3‐dihydro‐2H‐1,4‐benzodiazepin‐2‐one labeled with carbon‐14 in carbon 5 of the diazepine ring has been synthesized. The compound was prepared in a multistep synthesis from barium carbonate‐^14^C in an overall yield of 23%.
## Abstract (S)‐Fenvalerate (α‐cyano‐3‐phenoxybenzyl) (S)‐2‐(4‐chlorophenyl)‐3‐methylbutyrate, a novel insecticide, was labelled with carbon‐14 individually at the carbonyl (**1a**), the cyano (**1b**) and the alcoholic methyne (**1c**) carbons for use in metabolic studies. Isopropylation of 4‐chlo
## Abstract The preparation of ^14^C labelled 1‐(4‐chlorophenyl)‐2‐methy 1‐2‐aminopropane hydrochloride is described. The radioactive carbon was introduced into the central position of the aminopropyl group in order to study the pharmacological properties and mode of action of the anorexigenic drug