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Preparation of 2-methylenebutanedioic acid-4-14C (itaconic acid)

✍ Scribed by D. R. Campbell

Publisher
John Wiley and Sons
Year
1975
Tongue
French
Weight
180 KB
Volume
11
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

The pyrolysis of citric acid‐1, 5‐^14^C~2~ under controlled conditions and subsequent hydrolysis of the anhydride initially produced yields principally 2‐methylenebutanedioic acid‐4‐^14^C (citaconic acid‐^14^C), together with a minor amount of cis‐2‐methylbutenedioic acid‐4‐^14^C (citraconic acid‐^14^C). Comparison of the molar specific activities of the precursor and products indicates the absence of a carbon kinetic isotope effect in the decarboxylation‐dehydration reaction.

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