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The preparation and properties of thiophen analogues of porphyrins and related systems. Part II synthesis of porphyrinogen analogues

✍ Scribed by M. Ahmed; O. Meth-Cohn

Book ID
104239249
Publisher
Elsevier Science
Year
1969
Tongue
French
Weight
202 KB
Volume
10
Category
Article
ISSN
0040-4039

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✦ Synopsis

Although the ahemistry and synthesis of the porphyrin ring system has been intensively investigated for more than fifty years, no reports have yet appeared regarding its thiophen isosteres.

We report below the first syntheses of the thiophen isosteres of the porphyrinogen system (I).

πŸ“œ SIMILAR VOLUMES

Synthesis and Pharmacological Study of a
Synthesis and Pharmacological Study of a Thiophene Analogue of Moprolol and Related Compounds
✍ M. B. El-Ashmawy; J. Lissavetzky; V. Darias; D. MartΓ­n-Herrera πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 302 KB πŸ‘ 2 views

The syntheses of the thiophenic analogue of Moprolol (Id) and of its related compound l a are described. From a preliminary pharmacological evaluation compound Id seems worthy of further studies due to its notable P-blocking activity and its remarkable anti-platelet aggregation action. ## Synthese