CNQX, a new non-NMDA receptor antagonist
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G.M.J. Ramakers; B.W.M.M. Peeters; J.M.H. Vossen; A.M.L. Coenen
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Article
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1991
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Elsevier Science
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English
⚖ 330 KB
The effects on seizures, EEG and behavior of the non-NMDA receptor antagonist CNQX (6-cyano-7-nitroquinoxaline-2,3-dione), were studied in the WAG/Rij rat with absence epilepsy. Intracerebroventricular injections (10, 50, and 100 nmol/5 microliters CNQX) showed that CNQX decreases the number of spik