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Neuroactive steroids and GABAA receptor plasticity in the brain of the WAG/Rij rat, a model of absence epilepsy

✍ Scribed by Maria Giuseppina Pisu; Maria Cristina Mostallino; Riccardo Dore; Maria Luisa Mura; Elisabetta Maciocco; Emilio Russo; Giovambattista De Sarro; Mariangela Serra


Book ID
111181009
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
915 KB
Volume
106
Category
Article
ISSN
0022-3042

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CNQX, a new non-NMDA receptor antagonist
✍ G.M.J. Ramakers; B.W.M.M. Peeters; J.M.H. Vossen; A.M.L. Coenen πŸ“‚ Article πŸ“… 1991 πŸ› Elsevier Science 🌐 English βš– 330 KB

The effects on seizures, EEG and behavior of the non-NMDA receptor antagonist CNQX (6-cyano-7-nitroquinoxaline-2,3-dione), were studied in the WAG/Rij rat with absence epilepsy. Intracerebroventricular injections (10, 50, and 100 nmol/5 microliters CNQX) showed that CNQX decreases the number of spik