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The practical synthesis of RNA fragments in the solid phase approach

✍ Scribed by Hiroshi Tanimura; Tetsuya Fukazawa; Mitsuo Sekine; Tsujiaki Hata; J.William Efcavitch; Gerald Zon


Book ID
104216415
Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
146 KB
Volume
29
Category
Article
ISSN
0040-4039

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✦ Synopsis


The combined use of the 2'-tetrahydropyran-4-yl(Thp) group and 5 '-9-phenylxanthen-9-yl(Pix) group or (I-methoxy)phenyl xanthen-9-yl(Mox) group gave satisfactory results in the solid phase synthesis of medium sized RNA fragments.


πŸ“œ SIMILAR VOLUMES


Solid-phase synthesis of the RNA fragmen
✍ G. A. van der Marel; G. Wille; J. H. van Boom πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 634 KB

## Abstract The synthesis of the tridecaribonucleotide AAGAAGAAGAAGA on a polystyrene solid support via a phosphotriester approach is described. The assemblage of the oligomer was performed by four repeated coupling reactions of the partially protected trimer AAGp(3β€²) with an immobilized dimer in t