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The Power of Functional Resins in Organic Synthesis || Safety-Catch and Traceless Linkers in Solid Phase Organic Synthesis

✍ Scribed by Tulla-Puche, Judit; Albericio, Fernando


Book ID
120476996
Publisher
Wiley-VCH Verlag GmbH & Co. KGaA
Year
2008
Weight
714 KB
Category
Article
ISBN
3527319360

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πŸ“œ SIMILAR VOLUMES


Traceless Linkers-Only Disappearing Link
✍ Stefan BrΓ€se; Stefan Dahmen πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 304 KB πŸ‘ 2 views

Traceless linkers, which enable the attachment of arenes and alkanes to a polymeric support, have received increased attention in recent years. These anchoring groups allow chemical transformations on the polymer-bound molecules, which can be cleaved from the resin leaving no residual functionality

Safety-catch and multiply cleavable link
✍ Marcel PΓ‘tek; Michal Lebl πŸ“‚ Article πŸ“… 1998 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 176 KB

This review article focuses on concepts that incorporate safety-catch and multiply cleavable linkers in solid-phase synthesis. Discussed are specific applications of such linkers in the synthesis of peptides, peptide mimetics, and "small" organic molecules, as well as their limitations for particula