๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

The power comparison of the haplotype-based collapsing tests and the variant-based collapsing tests for detecting rare variants in pedigrees

โœ Scribed by Wei Guo,Yin Yao Shugart


Book ID
126370251
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
356 KB
Volume
15
Category
Article
ISSN
1471-2164

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


On the genome-wide analysis of copy numb
โœ Amy Murphy; Sungho Won; Angela Rogers; Jen-Hwa Chu; Benjamin A. Raby; Christoph ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 182 KB ๐Ÿ‘ 2 views

## Abstract We propose a new approach for the analysis of copy number variants (CNVs)for genomeโ€wide association studies in familyโ€based designs. Our new overall association test combines the betweenโ€family component and the withinโ€family component of the familyโ€based data so that the new test stat

Validity and power of association testin
โœ Stacey Knight; Nicola J. Camp ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 109 KB ๐Ÿ‘ 1 views

Current common wisdom posits that association analyses using family-based designs have inflated type 1 error rates (if relationships are ignored) and independent controls are more powerful than familial controls. We explore these suppositions. We show theoretically that family-based designs can have