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Weighted pedigree-based statistics for testing the association of rare variants

✍ Scribed by Yin Yao Shugart, Yun Zhu, Wei Guo, Momiao Xiong


Book ID
120676424
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
341 KB
Volume
13
Category
Article
ISSN
1471-2164

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In anticipation of the availability of next-generation sequencing data, there is increasing interest in investigating association between complex traits and rare variants (RVs). In contrast to association studies for common variants (CVs), due to the low frequencies of RVs, common wisdom suggests th