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The potential role of kynurenines in Alzheimer’s disease: pathomechanism and therapeutic possibilities by influencing the glutamate receptors

✍ Scribed by Majláth, Zsófia; Toldi, József; Vécsei, László

Book ID
121427398
Publisher
Springer
Year
2013
Tongue
English
Weight
274 KB
Volume
121
Category
Article
ISSN
1435-1463

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## Abstract Alzheimer's disease (AD) is a dementing neurodegenerative disorder without a cure. The abnormal parenchymal accumulation of β‐amyloid (Aβ) is associated with inflammatory reactions involving microglia and astrocytes. Increased levels of Aβ and Aβ deposition in the brain are thought to c