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The potential role of microRNA-146 in Alzheimer’s disease: Biomarker or therapeutic target?

✍ Scribed by Li-Ling Wang; Yue Huang; Gang Wang; Sheng-Di Chen

Book ID
116746303
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
210 KB
Volume
78
Category
Article
ISSN
0306-9877

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## Abstract Alzheimer's disease (AD) is a dementing neurodegenerative disorder without a cure. The abnormal parenchymal accumulation of β‐amyloid (Aβ) is associated with inflammatory reactions involving microglia and astrocytes. Increased levels of Aβ and Aβ deposition in the brain are thought to c