The role of theN-methyl-D-aspartate receptor in Alzheimer’s disease: Therapeutic potential
✍ Scribed by P. Murali Doraiswamy
- Book ID
- 107543245
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 361 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1528-4042
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## Abstract This study investigates the role of excitotoxicity in Alzheimer's disease and in multiinfarct dementia by examining, via immunohistochemical methods, the number of cells that are positive for N‐methyl‐D‐aspartate (NMDA) receptor and the degree of colocalization between NMDA receptor and
## Abstract Alzheimer's disease (AD) is a dementing neurodegenerative disorder without a cure. The abnormal parenchymal accumulation of β‐amyloid (Aβ) is associated with inflammatory reactions involving microglia and astrocytes. Increased levels of Aβ and Aβ deposition in the brain are thought to c