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The N-methyl-d-aspartate receptor complex in Alzheimer's disease: reduced regulation by glycine but not zinc

✍ Scribed by Janet E. Steele; Alan M. Palmer; Gary C. Stratmann; David M. Bowen


Book ID
115799251
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
408 KB
Volume
500
Category
Article
ISSN
0006-8993

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## Abstract The N‐methyl‐D‐aspartate receptor (NMDAR) is fundamental to normal and pathological functioning of neurons. The receptor subunits are N‐glycosylated proteins synthesized in the endoplasmic reticulum (ER) that fold, mature, and oligomerize as they transit through the secretory pathway. A