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The potential role of anibamine, a natural product CCR5 antagonist, and its analogues as leads toward development of anti-ovarian cancer agents

โœ Scribed by Yan Zhang; Christopher K. Arnatt; Feng Zhang; Jiannan Wang; Kendra M. Haney; Xianjun Fang


Book ID
116318639
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
255 KB
Volume
22
Category
Article
ISSN
0960-894X

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Accumulating evidence indicates that the chemokine receptor CCR5 and the chemokine CCL5 may be involved in the proliferation and metastasis of prostate cancer. Consequently, chemokine receptor CCR5 antagonists could potentially act as anti-prostate cancer agents. As the first natural product CCR5 an