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The natural product CCR5 antagonist anibamine and its analogs as anti-prostate cancer agents

โœ Scribed by Kendra M. Haney; Feng Zhang; Christopher K. Arnatt; Yunyun Yuan; Guo Li; Joy L. Ware; David A. Gewirtz; Yan Zhang


Book ID
113495987
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
219 KB
Volume
21
Category
Article
ISSN
0960-894X

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Anibamine, a natural product CCR5 antago
โœ Xueping Zhang; Kendra M. Haney; Amanda C. Richardson; Eden Wilson; David A. Gewi ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 874 KB

Accumulating evidence indicates that the chemokine receptor CCR5 and the chemokine CCL5 may be involved in the proliferation and metastasis of prostate cancer. Consequently, chemokine receptor CCR5 antagonists could potentially act as anti-prostate cancer agents. As the first natural product CCR5 an