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Structure activity relationship studies of natural product chemokine receptor CCR5 antagonist anibamine toward the development of novel anti prostate cancer agents

โœ Scribed by Zhang, Feng; Arnatt, Christopher K.; Haney, Kendra M.; Fang, Harrison C.; Bajacan, John E.; Richardson, Amanda C.; Ware, Joy L.; Zhang, Yan


Book ID
119234083
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
617 KB
Volume
55
Category
Article
ISSN
0223-5234

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Anibamine, a natural product CCR5 antago
โœ Xueping Zhang; Kendra M. Haney; Amanda C. Richardson; Eden Wilson; David A. Gewi ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 874 KB

Accumulating evidence indicates that the chemokine receptor CCR5 and the chemokine CCL5 may be involved in the proliferation and metastasis of prostate cancer. Consequently, chemokine receptor CCR5 antagonists could potentially act as anti-prostate cancer agents. As the first natural product CCR5 an