The potential inhibitory effect of antiparasitic drugs and natural products on P-glycoprotein mediated efflux
β Scribed by Rose Hayeshi; Collen Masimirembwa; Stanley Mukanganyama; Anna-Lena B. Ungell
- Book ID
- 113591670
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 408 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0928-0987
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We have previously reported that K562/ADM, a typical P-glycoprotein-mediated multi-drug-resistant cell line, is cross-resistant t o the growth-inhibitory effect of I 2 -0tetradecanoylphorbol I 3-acetate (TPA) and non-TPA type tumor promoters. To elucidate the mechanism of crossresistance to tumor pr