✦ LIBER ✦

Interaction of the P-Glycoprotein Multidrug Efflux Pump with Cholesterol: Effects on ATPase Activity, Drug Binding and Transport †

✍ Scribed by Eckford, Paul D. W.; Sharom, Frances J.

Book ID: 125516375
Publisher: American Chemical Society
Year: 2008
Tongue: English
Weight: 443 KB
Volume: 47
Category: Article
ISSN: 0006-2960
DOI: 10.1021/bi801409r

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Multidrug efflux pumps: The structures o

Multidrug efflux pumps: The structures of prokaryotic ATP-binding cassette transporter efflux pumps and implications for our understanding of eukaryotic P-glycoproteins and homologues

✍ Ian D. Kerr; Peter M. Jones; Anthony M. George 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 527 KB

Cholesterol-mediated activation of P-gly

Cholesterol-mediated activation of P-glycoprotein: Distinct effects on basal and drug-induced ATPase activities

✍ Sara Belli; Priska M. Elsener; Heidi Wunderli-Allenspach; Stefanie D. Krämer 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 353 KB

Cholesterol promotes basal and verapamil-induced ATPase activity of P-glycoprotein (P-gp). We investigated whether these effects are related to each other and to the impact of the sterol on bilayer fluidity and verapamil membrane affinity. P-gp was reconstituted in egg-phosphatidylcholine (PhC) lipo

MODULATION OF P-GLYCOPROTEIN ATPASE OF H

MODULATION OF P-GLYCOPROTEIN ATPASE OF HELICOVERPA ARMIGERA BY CHOLESTEROL: EFFECTS ON ATPASE ACTIVITY AND INTERACTION OF INSECTICIDES

✍ Ravindra M. Aurade; Senigala K. Jayalakshmi; Shashikant S. Udikeri; Kuruba Sreer 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 765 KB

New Insights into the Drug Binding, Tran

New Insights into the Drug Binding, Transport and Lipid Flippase Activities of the P-Glycoprotein Multidrug Transporter

✍ Frances J. Sharom; Miguel R. Lugo; Paul D. W. Eckford 📂 Article 📅 2005 🏛 Springer US 🌐 English ⚖ 113 KB

The P-glycoprotein multidrug transporter

The P-glycoprotein multidrug transporter: interactions with membrane lipids, and their modulation of activity

✍ Sharom, F. J. 📂 Article 📅 1997 🏛 Portland Press 🌐 English ⚖ 794 KB

DRUG-DRUG INTERACTION STUDIES OF CARDIOV

DRUG-DRUG INTERACTION STUDIES OF CARDIOVASCULAR DRUGS (AMIODARONE, DIGOXIN, QUINIDINE, ATORVASTATIN AND VERAPAMIL) INVOLVING P-GLYCOPROTEIN (P-GP), AN EFFLUX TRANSPORTER, ON THE PHARMACOKINETICS (PK) AND PHARMACODYNAMICS (PD) OF EDOXABAN, AN ORAL FACTOR XA INHIBITOR

✍ Mendell, Jeanne; Zahir, Halim; Ridout, Graham; Noveck, Robert; Lee, Frank; Chen, 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 253 KB