The Polymerase Chain Reaction (Nobel Lecture)
β Scribed by Dr. Kary B. Mullis
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 641 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
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A mathematical model for polymerase chain reaction (PCR) is developed, taking into account the three steps in this process: melting of DNA; primer annealing; and DNA synthesis (polymerization). Activity and deactivation of the polymerase enzyme as a function of temperature is incorporated in the kin