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The Plasminogen Activator System and Cancer

✍ Scribed by McMahon, Brandon; Kwaan, Hau C.

Book ID
119985014
Publisher
S. Karger AG
Year
2007
Tongue
English
Weight
338 KB
Volume
36
Category
Article
ISSN
1424-8832

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The urokinase-type plasminogen activator (u-PA) system consists of the serine proteinases plasmin and u-PA; the serpin inhibitors a 2 -anti-plasmin, PAI-1 and PAI-2; and the u-PA receptor (u-PAR). Two lines of evidence have strongly suggested an important and apparently causal role for the u-PA syst