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Clinical relevance of the urokinase plasminogen activator system in breast cancer

✍ Scribed by MAXIME P. LOOK; JOHN A. FOEKENS

Book ID
111277898
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
851 KB
Volume
107
Category
Article
ISSN
0365-5555

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✍ C. Duggan; T. Maguire; E. McDermott; N. O'Higgins; J. J. Fennelly; M. J. Duffy πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 French βš– 385 KB πŸ‘ 1 views

Urokinase plasminogen activator (uPA) is a serine protease involved in cancer invasion and metastasis. uPA mediates its action while attached to a membrane-bound receptor (uPAR). In this investigation we show that uPAR levels correlate with uPA levels in human breast cancers. uPAR levels, however, d