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The phosphorylation status of merlin in sporadic vestibular Schwannomas

✍ Scribed by Zhaoyan Wang; Yanjun Lu; Juanjuan Tang; Haojie Wang; Hao Wu


Book ID
106458484
Publisher
Springer
Year
2009
Tongue
English
Weight
232 KB
Volume
324
Category
Article
ISSN
0300-8177

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## Abstract Tumor‐specific alterations at the __p53__ gene locus in 30 human vestibular schwannomas (VS) comprising 10 confirmed NF2 cases and 20 sporadic cases were analyzed. We found loss of heterozygosity (LOH) at the first intron of the __p53__ gene locus in 54% of the informative cases. This i