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The perplexing role of copper-zinc superoxide dismutase in amyotrophic lateral sclerosis (Lou Gehrig's disease)

✍ Scribed by Soshanna Zittin Potter; Joan Selverstone Valentine


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
572 KB
Volume
8
Category
Article
ISSN
1432-1327

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Expression of the copper-zinc superoxide
✍ Kazutoshi Nishiyama; Dr. Shigeo Murayama; Shin Kwak; Ichiro Kanazawa πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 659 KB

## Abstract The demonstration of a genetic linkage between the copper‐zinc superoxide dismutase (SOD1) gene and familial amyotrophic lateral sclerosis has aroused interest in the role of SOD1 in motoneuronal death. We investigated the expression of the human SOD1 gene at a cellular level in the mot