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The pentylenetetrazole-kindling model of epilepsy in SAMP8 mice: behavior and metabolism

✍ Scribed by Daniel Kondziella; Abdel Bidar; Bente Urfjell; Olav Sletvold; Ursula Sonnewald

Book ID
117409732
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
61 KB
Volume
40
Category
Article
ISSN
0197-0186

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✍ O. Giorgi; G. Carboni; V. Frau; M. Orlandi; V. Valentini; A. Feldman; M. G. Cord πŸ“‚ Article πŸ“… 1996 πŸ› Springer-Verlag 🌐 English βš– 661 KB

The present study was designed to examine the ability of felbamate, a novel antiepileptic agent, to antagonize the increase in seizure severity (i.e., chemical kindling) produced by chronic treatment with initially subconvulsant doses of pentylenetetrazol (PTZ). Rats were treated with PTZ (30 mg/kg,